Bio-informatics, a rapidly evolving discipline is the application of computational tools & technique in the management and analysis of biological data. In particular, bio- informatics is often used when referring to the data and techniques used in large scale sequence, analysis of entire genome such as Arabidopsis, Homospiens etc. The main application of bioinfo is in data minig, analysis of data gathered in genome projects, sequence alignment protein structure prediction, phylogenetic, analysis and rational drug designing. In bio-info, the internet is used for public databases.